![]() Now look what have become the new top selling drugs in the world: antipsychotic drugs like Risperdal, Zyprexa, Abilify, Seroquel, Geodon and Invega. Often these individuals fail to realize that they are undergoing withdrawal and instead mistakenly conclude that they "need" the medication to control their original psychiatric problems. In addition to being largely ineffective, the antidepressants can be very distressing to withdraw from, which keeps the market artificially inflated by people who would desperately like to stop but find the process too emotionally or physically painful. Recent research examined all antidepressant studies submitted in recent years to FDA in regard to antidepressant efficacy and found that the drug performed no better than placebo except in "severely depressed patients," reaching "clinical significance" only "at the upper end of the very severely depressed category." Even then, the difference between the antidepressant and the placebo was "relatively small." Some studies suggest that the antidepressants are little or no more effective than a sugar pill and a lot more dangerous. Remember not so long ago when Prozac became the world's largest selling medication of any kind, and then for years how Prozac, Paxil and Zoloft took over many of the top 10 spots? Remember the explanations at the time–that they were wonder drugs and that 15-50 percent or more of Americans would need them some time in their lives? To many people this seemed like a scientific breakthrough when in reality it was … a triumph of marketing. At least 9 out of 10 adults I've seen in the last two decades who have suffered emotional episodes that could be diagnosed a s mania had them in direct response to stimulants or antidepressants–mostly the newer antidepressants starting with Prozac. Every single child I have evaluated who has suffered what looks like a manic episode has been taking stimulants or antidepressants, both of which cause mania. It's mostly about antidepressant-induced mania. Now psychiatric wards are filled with patients having their second and third or umpteenth manic episode and every psychiatrist's day is filled with patients diagnosed bipolar. When a person was admitted in a manic condition talking a mile a minute, imagining grand things about themselves, making outrageous plans, bursting with anger and energy, unable to sleep and otherwise euphoric, the condition was so unusual that we would hold grand rounds, a medical show-and-tell, to discuss the patient." In my four years of training, I saw one 19-year-old in a manic state and a few adults. Paragraphs 10 & 11 read: "When I took my psychiatric residency at Harvard in Boston and at SUNY in Syracuse in the early 1960s, we never saw or diagnosed bipolar disorder in children.
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